Endocrine Abstracts

The relation between sexual and cardiovascular health in women is not well defined. Clitoral colour Doppler ultrasound (CDU) with assessment of the pulsatility index (PI), reflecting resistance to blood flow, has been proposed as an objective measurement of sexual functioning. We aimed to investigate the associations between clitoral PI and cardiometabolic risk factors. Seventy-one adult heterosexual women attending our clinic for sexual dysfunction were consecutively recruite...

PCOS (Polycystic Ovary Syndrome) is one of the most common endocrine disorders and NAFLD (Nonalcoholic Fatty Liver Disease) is one of its most dangerous metabolic consequences. The diagnosis of NAFLD is not a practical task and the condition is at risk of being overlooked. The use of simpler but still reliable surrogate markers is necessary to identify women with a high likelihood of NAFLD. The aim of this study was to evaluate the clinical correlates of NAFLD Liver Fat Score ...

BackgroundResearch on the relationship between physical activity (PA) and female sexual dysfunction (FSD) is lacking.AimTo investigate the clinical, psychological, and sexual correlates of PA in women with FSD.MethodsA non-selected series of n = 322 pre- and post-menopausal patients consulting for FSD was retrospectively studied. Regular involvement in PA...

PurposeObjective of this study was to assess the association between testosterone (T) levels and biochemical markers in a cohort of female patients admitted for SARS-CoV-2 infection in a respiratory intensive care unit (RICU).MethodsA consecutive series of 17 women affected by SARSCoV-2 pneumonia and recovered in the RICU of the Hospital of Mantua (Italy) were analyzed. Biochemical inflammatory markers as wel...

In this study, we investigated steroidogenic gene mRNA expression in human vagina and verified the ability of human vagina smooth muscle cells (hvSMCs) to synthesize androgens from upstream precursor dehydroepiandrosterone (DHEA). As a readout for androgen receptor (AR) activation, we evaluated the mRNA expression of various androgen-dependent markers. hvSMCs were isolated from vagina tissues of women undergoing surgery for benign gynecological diseases. In these cells, we eva...